anti BDNF antibody, anti mature BDNF antibody, anti Brain derived neurotrophic factor antibody, Abrineurin antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSB00022W

$260USD

ID Tag

Sh274-051217-WS

Immunogen

A synthetic peptide from mature BDNF conjugated to blue carrier protein was used as the antigen. The peptide is homologous in many other species including rat, mouse, zebra fish and xenopus.

Accession

BDNF_HUMAN
BDNF_RAT
BDNF_MOUSE

Also known

Brain-derived neurotrophic factor, BDNF, Abrineurin

Target

FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB.
SUBCELLULAR LOCATION: Secreted.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Maisonpierre P.C, et al. Genomics 10:558-568(1991).

Limitation

For research use only

Related
products

Code	Product Name
OSB00023G	Sheep antibody to BDNF
OSB00026A	Sheep antibody to BDNF

Code

OSB00022W

$260USD

Unit size

100 ul

Conjugate

Unconjugated antibody

Host

Sheep

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for mature BDNF.

Spcs X-react.

Human, rat, mouse, marmoset. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Code

GSB00003P

$120USD

ID Tag

50278-16

Unit size

50 Âµg

Accession

BDNF_HUMAN
BDNF_RAT
BDNF_MOUSE

Also known

Brain derived neurotrophic factor, BDNF, Abrineurin

Target

This is the immunising peptide for the product Sheep antibody to n-terminal region of mature BDNF (Brain derived neurotrophic factor): IgG (OSB00023G) and Sheep antibody to n-terminal region of mature BDNF (Brain derived neurotrophic factor): whole serum (OSB00022W)

Purity

>87%

Applications

Control peptide

Format

Lyophilised

Reconstitution

This peptide is soluble in PBS and water.

Storage

Maintain refrigerated at 2-8°C for up to 12 months. After reconstitution keep at -20°C. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

Limitation

For research use only