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Code
OST00197W
$240USD
ID Tag
Rb618-170808-WS
Immunogen
A synthetic peptide from aa region 10-60 of rat TRPC6 conjugated to blue carrier protein was used as the antigen. The antigen is homologous with the corresponding sequence in mouse.
The location of the epitope is highlighted in green.
The location of the epitope is highlighted in green.
Accession
Also known
Short transient receptor potential channel 6, TrpC6, Calcium entry channel, Trp6, transient receptor potential cation channel, subfamily C, member 6, Trrp6, mtrp6
Target
FUNCTION: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Boulay G, et al. J. Biol. Chem. 272:29672-29680(1997).
2. Buess M, et al. Oncogene 18:1487-1494(1999).
2. Buess M, et al. Oncogene 18:1487-1494(1999).
Limitation
For research use only
Related
products
products
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Code
OST00197W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
WB. A dilution of 1: 4000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for TRPC6.
Spcs X-react.
Mouse, rat, human, marmoset. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
- Click to see the eLab Book
Code
OST00197W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OST00197W
$240USD
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WB on rat tissue lysates. Blocking: 1% LFDM for 30 min at RT; primary antibody: dilution 1:4000 incubated at 4C overnight. Click on eLAB BOOK tab to see the details. |
⚬ Products
Rabbit antibody to TRPC6 (10-60)
