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Code
OSB00020W
$260USD
ID Tag
Rb3148-241117-WS
Immunogen
A synthetic peptide from human Beclin1 conjugated to blue carrier protein has been used as the antigen. The peptide is homologous in rat and mouse.
Accession
Also known
Beclin-1, BECN1, GT197, ATG6, VPS30, beclin1
Target
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. It may play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus. May play a role in autophagy.
SUBCELLULAR LOCATION: Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Note: Expressed in dendrites and cell bodies of cerebellar Purkinje cells
TISSUE SPECIFICITY: Ubiquitous
SUBCELLULAR LOCATION: Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Note: Expressed in dendrites and cell bodies of cerebellar Purkinje cells
TISSUE SPECIFICITY: Ubiquitous
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Feng W, et al. J. Mol. Biol. 372 (1), 223-235(2007).
Limitation
For research use only
Code
OSB00020W
$260USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. Use at a dilution of 1 : 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Beclin1.
Spcs X-react.
Human, mouse, rat, marmoset. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
- Click to see the eLab Book
Code
OSB00020W
$260USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSB00020W
$260USD
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WB on tissue lysates. Blocking: 1% LFDM for 30 min at RT; primary antibody: dilution 1:2000 incubated overnight at 4C. Click on eLAB BOOK tab to see the details. |
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WB on tissue lysates. Blocking: 1% LFDM for 30 min at RT; primary antibody: dilution 1:2000 incubated overnight at 4C. Click on eLAB BOOK tab to see the details. |
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WB on tissue lysates. Blocking: 1% LFDM for 30 min at RT; primary antibody: dilution 1:2000 incubated overnight at 4C. Click on eLAB BOOK tab to see the details. |
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WB on tissue lysates. Blocking: 1% LFDM for 30 min at RT; primary antibody: dilution 1:2000 incubated overnight at 4C. Click on eLAB BOOK tab to see the details. |
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Rabbit antibody to Beclin1
