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Code
OST00155W
$240USD
ID Tag
Rb503-290608-WS
Immunogen
A synthetic peptide from the 1t lumenal part of human transmembrane channel-like protein 6 (TMC6, EVER1, Protein LAK-4, EVIN1) conjugated to an immunogenic carrier protein was used as the immunogen.
Accession
Also known
TMC6, EVER1, Epidermodysplasia verruciformis protein 1, Protein LAK-4, EVIN1
Target
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed in placenta, prostate, testis, activated T-lymphocytes and lymphokine-activated killer (LAK) lymphocytes.
DISEASE: Defects in TMC6 are a cause of epidermodysplasia verruciformis. It is a rare autosomal recessive genodermatosis associated with a high risk of skin carcinoma that results from an abnormal susceptibility to infection by specific human papillomaviruses. Infection leads to persistent wart-like or macular lesions.
TISSUE SPECIFICITY: Expressed in placenta, prostate, testis, activated T-lymphocytes and lymphokine-activated killer (LAK) lymphocytes.
DISEASE: Defects in TMC6 are a cause of epidermodysplasia verruciformis. It is a rare autosomal recessive genodermatosis associated with a high risk of skin carcinoma that results from an abnormal susceptibility to infection by specific human papillomaviruses. Infection leads to persistent wart-like or macular lesions.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Ramoz N, et al. Nat. Genet. 32:579-581(2002).
2. Kurima K, et al. Genomics 82:300-308(2003).
3. Ota T, et al. Nat. Genet. 36:40-45(2004).
4. Tate G, et al. J. Hum. Genet. 49:223-225(2004).
5. Olsen J.V, et al. Cell 127:635-648(2006).
2. Kurima K, et al. Genomics 82:300-308(2003).
3. Ota T, et al. Nat. Genet. 36:40-45(2004).
4. Tate G, et al. J. Hum. Genet. 49:223-225(2004).
5. Olsen J.V, et al. Cell 127:635-648(2006).
Limitation
For research use only
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Code
OST00155W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
Specificity
Specific for TMC6.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OST00155W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
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Rabbit antibody to TMC6
