TMC8 antibody, EVER2 antibody, transmembrane channel-like protein 8 antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OST00151W

$260USD

ID Tag

Rb487-290608-WS

Immunogen

A synthetic peptide from the 1t cytoplasmic loop of human transmembrane channel-like protein 8 (TMC8, EVER2, EVIN2) conjugated to blue carrier protein was used as the antigen.

Accession

TMC8_HUMAN

Also known

TMC8, Epidermodysplasia verruciformis protein 2, EVER2, EVIN2

Target

SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed in placenta, prostate and testis.
DISEASE: Defects in TMC8 are a cause of epidermodysplasia verruciformis. It is a rare autosomal recessive genodermatosis associated with a high risk of skin carcinoma that results from an abnormal susceptibility to infection by specific human papillomaviruses. Infection leads to persistent wart-like or macular lesions.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Ramoz N, et al. Nat. Genet. 32:579-581(2002).

Limitation

For research use only

Related
products

Code	Product Name
OST00152W	Rabbit antibody to TMC8

Code

OST00151W

$260USD

Unit size

100 ul

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for TMC8.

Spcs X-react.

Human. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OST00151W