RACK1 antibody, GNB2L1 antibody, GBLP antibody, Receptor for activated C kinase antibody

Primary Antibodies

ABC Transporters

Autophagy

Cancer

Cellular

Immunology

Reporter Genes & Tags

Reproduction

SLC & Regulators

Subcellular Markers

Toxins

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSG00019W

$240USD

ID Tag

Rb526-290608-WS

Immunogen

A synthetic peptide from the internal region of human RACK1 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in many species including rat, mouse and xenopus.

Accession

GBLP_HUMAN
GBLP_RAT
GBLP_MOUSE
GBLP_XENOPUS

Also known

Guanine nucleotide-binding protein subunit beta-like protein 12.3, Receptor of activated protein kinase C 1, RACK1, Receptor for activated C kinase, Guanine nucleotide-binding protein subunit beta-2-like 1, GNB2L1

Target

Function: Seems to bind protein kinase C acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and ITGB1, serves as a platform for SRC activation or inactivation. May play an important role in the developing brain and neuronal differentiation.
Subcellular location: Cell membrane. Note: Located on plasma membrane of neuroblastoma NMB7 cells.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Guillemot F, et al. Proc. Natl. Acad. Sci. U.S.A. 86:4594-4598(1989)
2. Nery F.C, et al. J. Biol. Chem. 279:11444-11455(2004)

Limitation

For research use only

Code

OSG00019W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for GBLP.

Spcs X-react.

Human, rat, mouse. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSG00019W