|
|
Code
OSV00011G
$240USD
ID Tag
Sh91-290608-G
Immunogen
A synthetic peptide from human VAMP3 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
Accession
Also known
VAMP-3, VAMP3, Synaptobrevin-3, Cellubrevin, SYB3, CEB
Target
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation.
FUNCTION: Trafficking protein from a constitutively recycling pathway.
SUBCELLULAR LOCATION: Membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome.
FUNCTION: Trafficking protein from a constitutively recycling pathway.
SUBCELLULAR LOCATION: Membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Bernstein A.M, et al. Blood 93:571-579(1999).
2. Gregory S.G, et al. Nature 441:315-321(2006).
3. Gevaert K, et al. Nat. Biotechnol. 21:566-569(2003).
2. Gregory S.G, et al. Nature 441:315-321(2006).
3. Gevaert K, et al. Nat. Biotechnol. 21:566-569(2003).
Limitation
For research use only
Related
products
products
|
Code
OSV00011G
$240USD
Unit size
500 µg
Conjugate
Unconjugated antibody
Host
Sheep
Purity
IgG
Clonality
Polyclonal
Isotype
Polyclonal, IgG
Applications
IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for VAMP3.
Spcs X-react.
Human, rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSV00011G
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Sheep antibody to VAMP 3
